Saskatchewan Centre for Cyclotron Sciences (SCCS)
A World-Class Facility for Nuclear Imaging, Discovery and Innovation
This state-of-the-art facility is owned by the University of Saskatchewan and operated by the Fedoruk Centre to support innovation in nuclear imaging and therapy in living specimens: plants, animals and humans.
What You Can Do at the SCCS
The SCCS is a Class II nuclear facility licensed by the Canadian Nuclear Safety Commission (CNSC) to produce and handle a wide range of isotopes. The SCCS has the flexibility to broaden its product portfolio in response to researchers' emerging requirements. Specialized radiochemical and radioanalytical workstations allow for the synthesis, separation, purification, and characterization of radiolabelled compounds. Environmentally controlled clean space is available for developing radiotracers in conditions compliant with Good Manufacturing Practices (GMP).
The SCCS houses equipment suitable for validating new therapeutic molecules and imaging agents through ‘in vitro’ and ‘in vivo’ experiments. The cell culture laboratory accommodates the growth of cell lines needed for a study. Small animal SPECT/CT, and PET/CT imaging equipment are available to evaluate the response in animal models. Radiation counters and detectors for alpha, beta and gamma radiations are available for use in biodistribution studies
The BioPETx detector—first of its kind in Canada—is used to study plants and soil under various conditions and detect responses to stressors such as drought, infections, and insect infestations. Growth chambers are available to control environmental conditions and safely house dosed plants.
The Fedoruk Centre holds a Drug Establishment Licence (DEL) issued by Health Canada to produce fluorodeoxyglucose (FDG) as a marketed drug product at the SCCS. Our highly qualified staff is ready to assist you in validating GMP compliant procedures and conducting Quality Control testing.
The Fedoruk Centre staff at the SCCS will work with your team to demonstrate and explain the cutting-edge equipment available to you as a user. Training is available for team members who are newly accessing a workstation, to ensure they begin projects with fundamental knowledge of each instrument, at no charge to a specific research project. Our equipment includes HPLC, GC, hot cells, synthesizers, radioTLC, SPECT/PET/CT and optical imagers, contamination monitors and more. For specific research projects, direct support of expert staff can also be arranged as a service within a user-access agreement.
How to Access the SCCS
- See the spreadsheet Workstation Occupancy Estimator for a current list of SCCS workstations, equipment and hourly rates for research that generates knowledge in the public or private domain.
- Submit a proposal to the Fedoruk Centre for a project utilizing the SCCS. See forms HS-COF-0048 (the Research Permit Application) and HS-COF-0072 (the Research Project Application). Upon request of these forms, the SCCS Facility General Manager will assign a Local Contact to help you plan your project and coordinate resources. The hand-out Process for the Submission of Users Proposals at SCCS will guide you through the steps.
- Establish a contractual relationship with the Fedoruk Centre.
USask Researchers - Request a procurement agreement/amendment between USask and the Fedoruk Centre for SCCS Access. See USask Researcher Guide to Engaging the Fedoruk Centre (November 15, 2020)